This map of the Florida Keys shows all the islands and mile markers from Key Largo down to Key West. We also have a street map of Key West that shows all the hotels so you can find a place to stay near Duval St. US Route 1 is the Overseas Highway and the only road that you can drive down from the mainland. The reef runs alongside just a few miles off shore and we have marked all of the most popular dive locations along the route. It’s about 110 miles and often considered one of the best drives in the world. As you come down over the bridges and look out over the clear blue waters, it is really breath taking.